- Original Article
- Gastroenterology
- Influence of proton pump inhibitor therapy on intestinal inflammation assessed by fecal calprotectin in pediatric patients
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Su Yeong Kim, Na Mi Lee, Sin Weon Yun, Soo Ahn Chae, In Seok Lim, Eung Sang Choi, Dae Yong Yi
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Clin Exp Pediatr. 2019;62(10):400-404. Published online July 3, 2019
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Background: An increase in the numbers of patients with gastrointestinal symptoms has recently been observed.
Purpose: To investigate the effects of proton pump inhibitor (PPI) therapy on intestinal inflammation in children and adolescents as confirmed by clinical manifestations and objectively assessed by fecal calprotectin (FC) level measurement.
Methods: Consecutive children (aged 3–18 years) who presented with gastrointestinal symptoms and were treated with... |
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- Neuroprotective effects of mild hypoxia in organotypic hippocampal slice cultures
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Seh Hyun Kim, Woo Soon Lee, Na Mi Lee, Soo Ahn Chae, Sin Weon Yun
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Clin Exp Pediatr. 2015;58(4):142-147. Published online April 22, 2015
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Purpose The aim of this study was to investigate the potential effects of mild hypoxia in the mature and immature brain. MethodsWe prepared organotypic slice cultures of the hippocampus and used hippocampal tissue cultures at 7 and 14 days in vitro (DIV) to represent the immature and mature brain, respectively. Tissue cultures were exposed to 10% oxygen for 60 minutes. Twenty-four hours... |
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- Susceptibility of rat hippocampal neurons to hypothermia during development
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Kyung Ah Seo, Sehhyun Kim, Na Mi Lee, Soo Ahn Chae
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Clin Exp Pediatr. 2013;56(10):446-450. Published online October 31, 2013
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Purpose This study evaluated the extent of damage due to hypothermia in the mature and immature brain. MethodsHippocampal tissue cultures at 7 and 14 days in vitro (DIV) were used to represent the immature and mature brain, respectively. The cultures were exposed at 25℃ for 0, 10, 30, and 60 minutes (n=30 in each subgroup). Propidium iodide fluorescent images were captured 24... |
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- Comparison of various methods of glomerular filtration rate measurements in children
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Na Mi Lee, In Seok Lim
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Clin Exp Pediatr. 2009;52(9):999-1004. Published online September 15, 2009
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Purpose:Glomerular filtration rate (GFR) is a fundamental parameter in assessing renal function and predicting the progression of chronic renal disease. Because the use of serum creatinine has several disadvantages, many studies have investigated the use of cystatin C for estimating GFR. We compared creatinine clearance and GFR with formulas using serum creatinine and cystatin C.
Methods:We retrospectively analyzed 211 patients... |
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